Dr. White is head of the Drug Metabolism and Pharmacokinetics Department at the Schering-Plough Research Institute. His function is to provide information on the animal and human metabolism, disposition and pharmacokinetics of investigational molecules to support their selection for clinical development and their registration as new medicines with worldwide regulatory authorities. In addition, Dr. White conducts basic research in the following areas:

(1) CYP induction – homology modeling of the Constitutively Active Receptor (CAR): crystallography of the Pregnane X Receptor (PXR); creation and evaluation of expressed reporter-gene models CYP induction;

(2) intestinal absorption mechanisms of drugs;

(3) reactive metabolites of drugs;

(4) pharmacokinetic theory.

	Whatever happened to cassette-dosing pharmacokinetics? Manitpisitkul P, White RE. Drug Discov Today. 2004 Aug 1;9(15):652-8.
	Development of a screening assay to measure the loss of antibacterial activity in the presence of proteins: its use in optimizing compound structure. Roychoudhury S, Brill JL, Lu WP, White RE, Chen Z, Demuth TP Jr. J Biomol Screen. 2003 Oct;8(5):555-8.
	A high-throughput cell-based reporter gene system for measurement of CYP1A1 induction. Cui X, Palamanda J, Norton L, Thomas A, Lau YY, White RE, Cheng KC. J Pharmacol Toxicol Methods. 2002 May-Jun;47(3):143-51.
	Semi-automated determination of plasma stability of drug discovery compounds using liquid chromatography-tandem mass spectrometry. Wang G, Hsieh Y, Lau Y, Cheng KC, Ng K, Korfmacher WA, White RE. J Chromatogr B Analyt Technol Biomed Life Sci. 2002 Nov 25;780(2):451-7.