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Chemistry : EPR studies of free radical intermediates and their reactions, particularly of lipids; metal-lipid and chelator-lipid interactions; co-oxiations of proteins and nucleic acids by oxidizing lipids; mechanisms of initiations; electrochemistry of protic versus aprotic lipids; metal and heme catalysis; phase effects (aqueous versus lipid versus mixed) on kinetics and mechanisms; development of supercritical fluid extractions of lipids; free radical chemistry of natural antioxidants; stability of medium chain triglycerides and structured lipids.
Biochemistry : factors affecting oxidative stability of membranes, cells, and tissues; cellular repair of oxidative damage; lipids and signal transduction under oxidative stress; relationships of heme protein, transferrin, and ferrin to lipid oxidation in living cells and in muscle tissue post-slaughter
Food Science : EPR studies of free radicals in foods; lipid free radical versus lipid oxidation product interactions with proteins and carbohydrates in the oxidative deteriorations of foods; relationships of phase metal, and moisture to lipid oxidation in foods; free radical chemistry of natural phenolic antioxidants; natural photosensitizers; design of new phase-specific chelators and antioxidantsfor use in foods; development of methods for demetalling food oils and for recovering useable fractions of abused, heated oils; heme and metal catalysis of oxidations in muscle foods; free radical chemistry of proteins and starches in extruded products; development of new HPLC and chemiluminescence analyses of lipid oxidation; supercritical fluid extraction of lipids from low-lipid food products; fat substitutes
Toxicology and Medicine : lipid co-oxidation of proteins and nucleic acids in oxidative cytotoxicity, disease, and cancer; heme and metal catalysis of lipid oxidation in vivo; detection and accurate measurement of early stages of lipid oxidation in tissues and in vivo; free fatty acids, metals, and lipid oxidation in myelindegenerative diseases.
Nutrition : effect of dietary lipid and pro- or anti- oxidants on oxidative stablility of membranes; effect of diet on response to oxidative stress; toxicity of dietary oxidized lipids.
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Partridge, M.A.K., Jiang, Y., Skerritt, J.H., and Schaich, K.M. 2003. Immunochemical and electrophoretic analysis of soluble modified proteins in extruded wheat flour. Cereal Chemistry 80 (6): 791-798. |
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Schaich, K. M. 2002, EPR methods for detecting and identifying free radicals in foods, in Free Radicals in Foods: Chemistry, Nutrition, and Health, American Chemical Soc, Washington, D.C. pp. 12-34. |
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Schaich, K.M. 2002. Free radical generation during extrusion: a critical contributor to texturization, in Free Radicals in Foods: Chemistry, Nutrition, and Health, American Chemical Soc., Washington, D.C., pp. 35-48 |
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Schaich, K.M. 2002. NO* production during thermal processing of beef: evidence for protein oxidation, in Free Radicals in Foods: Chemistry, Nutrition, and Health, American Chemical Soc., Washington, D.C., pp. 151-161. |
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