We are interested in the toxic and carcinogenic effects of benzene, the specific metabolites of benzene necessary for the production of toxic effects and how they alter the function of progenitor and micro-environmental cells in the bone marrow, as well as determining which bone marrow cell types are most susceptible to benzene and how benzene produces aplastic anemia and leukemia.

	Inhibition of topoisomerase II in 32D.3(G) cells by hydroquinone is associated with cell death. Fung J, Hoffmann MJ, Kim DD, Snyder R. J Appl Toxicol. 2004 May-Jun;24(3):183-8.
	Metabolic and biochemical issues in the molecular epidemiology of cancer. Snyder R, Hong JY. IARC Sci Publ. 2004;(157):51-69.
	Benzene and leukemia. Snyder R. Crit Rev Toxicol. 2002 May;32(3):155-210.
	Cytochrome P450, the oxygen-activating enzyme in xenobiotic metabolism. Snyder R. Toxicol Sci. 2000 Nov;58(1):3-4.